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The steroid is indeed powerful as an anti-inflammatory, but the numerous side effects make it a medication that is not good for long term usesand is best used in combination with a well-formulated steroidal-based pain management program, Dr. Levey said. "There may be some potential for problems, but it is not like taking a stimulant and becoming an amputee," he said. Dr. Peter Levey, Professor of Pain Management, University of Birmingham, Birmingham In response to the article, Dr. Llewellyn-Jones, of University Hospitals of North Midlands NHS Trust in Birmingham, said: "There is nothing inherently wrong with the drug (sodium oxybate) itself. It is a very safe anti-inflammatory. In the vast majority of cases where someone develops a serious side effect to this drug, this is usually related to inappropriate use. "The article shows that there has been a lack of knowledge about the drug, and that doctors need to be aware of this to be able to provide appropriate advice in the event of a problem." How to be certain that a patient will benefit from anti-inflammatory medication is not as straightforward as people tend to imagine, Dr. Levey said. For patients who do have a significant, life threatening effect from their steroidal-based pain management, the first step is always to carry out a medical review so we can discuss the likely benefits and risks with them. This will ensure that the right treatment is appropriate and it also is vital to understand the severity of the disease, which is known to be influenced by genetics – a fact that must be taken into account when considering the likelihood of a treatment success, he said. Other medications which have anti-inflammatory properties often have other, often undesired side effects. "It is important that we look at the whole picture and take all the appropriate measures if any side–effects seem problematic," Dr. Levey concluded. Related Article: